Iron overload disorders can lead to the overaccumulation of iron in various organs, but the liver is one of the most commonly affected organs.
The liver is the main location for iron storage in the body, hence it is frequently the first organ to be impacted by iron excess. Over time, high iron buildup in the liver can lead to:
Liver enlargement (hepatomegaly)
Liver fibrosis and cirrhosis: This can cause scarring of the liver tissue.
Liver cancer (Hepatocellular carcinoma): In severe cases, persistent iron overload raises the risk of liver cancer.